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Western blot analysis of extracts from HepG2 cells treated with TNF using IKK- alpha/ beta (Phospho-Ser180/181) antibody P40569.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to IKK- alpha/ beta (Phospho-Ser180/181)

货号：
P40569
别名：
FLJ40509; I-kappa-B kinase; IKBKB; kinase beta; NFKBIKB
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O15111
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to IKK- alpha/ beta (Phospho-Ser180/181)

Description
Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.Hafeez BB, et al. (2008) Cancer Res 68, 8564-72 Cahill CM, Rogers JT (2008) J Biol Chem 283, 25900-12 Encinas M, et al. (2008)Cell Death Differ 15, 1510-21

Description

Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.Hafeez BB, et al. (2008) Cancer Res 68, 8564-72 Cahill CM, Rogers JT (2008) J Biol Chem 283, 25900-12 Encinas M, et al. (2008)Cell Death Differ 15, 1510-21

Specification
Aliases	FLJ40509; I-kappa-B kinase; IKBKB; kinase beta; NFKBIKB
Entrez GeneID	1147;
Swissprot	O15111
WB Predicted band size	85kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 180/181 (C-T-S(p)-F-V) derived from Human IKK- alpha/ beta.
Formulation	Purified antibody in PBS with 0.05% sodium azide.