Rabbit Polyclonal Antibody to Smad2 (Phospho-Ser250)

Description
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.

References
Fransvea E, Mazzocca A, Antonaci S, Giannelli G (2009)Hepatology 49, 839-50 . Funaba M, Zimmerman CM, Mathews LS (2002)J Biol Chem 277, 41361-8. Kretzschmar M, Doody J, Timokhina I, Massagu篓娄 J (1999)Genes Dev 13, 804-16 .

Specification
Aliases	JV18-1; MADH2; Mad-related protein 2; Mothers against DPP homolog 2;
Entrez GeneID	4087;
Swissprot	Q15796
WB Predicted band size	65kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine250(E-L-S(p)-P-T) derived from Human Smad2 .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000