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Rabbit Polyclonal Antibody to PKCD (Phospho-Tyr64)
Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) antibody P40561.The lane on the right is treated with the antigen-specific peptide.
Rabbit Polyclonal Antibody to PKCD (Phospho-Tyr64)

Rabbit Polyclonal Antibody to PKCD (Phospho-Tyr64)

  • 货号:

    P40561
  • 别名:

    KPCD; PKC-delta; PRKCD; kinase PKC-delta; nPKC-delta
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q05655
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to PKCD (Phospho-Tyr64)

Description

Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 283, 17731-9.

Specification

Aliases KPCD; PKC-delta; PRKCD; kinase PKC-delta; nPKC-delta
Entrez GeneID 5580;
Swissprot Q05655
WB Predicted band size 78kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen Peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y(p)-E-G) derived from Human PKCD.
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40561