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Rabbit Polyclonal Antibody to FAK (Phospho-Ser843)

Western blot analysis of extracts from 3T3 cells treated with PMA using Phospho-FAK (Ser843) antibody P40560.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to FAK (Phospho-Ser843)

货号：
P40560
别名：
FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
Q05397
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to FAK (Phospho-Ser843)

Description
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Description

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

References
Jiang X, Sinnett-Smith J, Rozengurt E (2007)Cell Signal 19, 1000-10 . Jacamo R, Jiang X, Lunn JA, Rozengurt E (2007)J Cell Physiol 210, 436-44. Le Boeuf F, Houle F, Sussman M, Huot J (2006)Mol Biol Cell 17, 3508-20 .

Specification
Aliases	FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK
Entrez GeneID	5747;
Swissprot	Q05397
WB Predicted band size	120kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Peptide sequence around phosphorylation site of serine843(R-G-S(p)-I-D) derived from Human FAK .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.