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Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)
Western blot analysis of extracts from COS7 cells treated with EGF using Phospho-CDK5 (Tyr15) antibody P40558.The lane on the right is treated with the antigen-specific peptide.
Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)

Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)

  • 货号:

    P40558
  • 别名:

    CDK5; CRK6; Cell division protein kinase 5; Tau protein kinase II catalytic subunit; kinase Cdk5
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q00535
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)

Description

Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Miao Y, et al. (2012)PLoS One 7, e42318. Li P, et al. (2011)Cell 147, 815-26. Nohara A, et al. (2011)J Biol Chem 286, 33457-65.

Specification

Aliases CDK5; CRK6; Cell division protein kinase 5; Tau protein kinase II catalytic subunit; kinase Cdk5
Entrez GeneID 1020;
Swissprot Q00535
WB Predicted band size 33kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of Tyrosine15 (G-T-Y(p)-G-T) derived from Human CDK5.
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40558