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Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)
-
货号:
P40558 -
别名:
CDK5; CRK6; Cell division protein kinase 5; Tau protein kinase II catalytic subunit; kinase Cdk5 -
应用:
WB -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q00535 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Rabbit Polyclonal Antibody to CDK5 (Phospho-Tyr15)
Description |
|---|
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Miao Y, et al. (2012)PLoS One 7, e42318. Li P, et al. (2011)Cell 147, 815-26. Nohara A, et al. (2011)J Biol Chem 286, 33457-65. |
Specification |
|
|---|---|
| Aliases | CDK5; CRK6; Cell division protein kinase 5; Tau protein kinase II catalytic subunit; kinase Cdk5 |
| Entrez GeneID | 1020; |
| Swissprot | Q00535 |
| WB Predicted band size | 33kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine15 (G-T-Y(p)-G-T) derived from Human CDK5. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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