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Rabbit Polyclonal Antibody to PDGFRa (Phospho-Tyr849)

Western blot analysis of extracts from 293 tissue using PDGFRa (Phospho-Tyr849) antibody P40552.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to PDGFRa (Phospho-Tyr849)

货号：
P40552
别名：
CD140a; PDGFR-alpha; PGFRA; kinase PDGFR-alpha;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P16234
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to PDGFRa (Phospho-Tyr849)

Description
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Rikova K, et al. (2007) Cell 131, 1190-203 Moritz A, et al. (2010) Sci Signal 3, ra64 Guo A, et al. (2008) Proc Natl Acad Sci U S A 105, 692-7

Description

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Rikova K, et al. (2007) Cell 131, 1190-203 Moritz A, et al. (2010) Sci Signal 3, ra64 Guo A, et al. (2008) Proc Natl Acad Sci U S A 105, 692-7

Specification
Aliases	CD140a; PDGFR-alpha; PGFRA; kinase PDGFR-alpha;
Entrez GeneID	5156;
Swissprot	P16234
WB Predicted band size	140kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of Tyrosine849(S-N-Y(p)-V-S) derived from Human PDGFRa.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.