Rabbit Polyclonal Antibody to HER2 (Phospho-Tyr1112)

Description
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.

References
Chuang TD, et al. (2010)J Biol Chem 285, 23598-606 Bhuvaneswari R, Gan YY, Soo KC, Olivo M (2009) Mol Cancer 8, 94 Thelemann A, et al. (2005) Mol Cell Proteomics 4, 356-76

Specification
Aliases	C-erbB-2; NGL; NEU proto-oncogene; MLN 19;
Entrez GeneID	2064;
Swissprot	P04626
WB Predicted band size	150kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y(p)-S-E) derived from Human HER2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000