Rabbit Polyclonal Antibody to Smad2 (Phospho-Ser465)

Description
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.Riggins G.J., Nat. Genet. 13:347-349(1996)Zhang Y., Nature 383:168-172(1996)Eppert K., Cell 86:543-552(1996)

Specification
Aliases	hMAD-2; JV18; JV18-1; MAD; hSMAD2
Entrez GeneID	4087;
Swissprot	Q15796
WB Predicted band size	52kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Serine 465(C-S-S(p)-M-S) derived from Human Smad2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000