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Rabbit Polyclonal Antibody to HCK (Phospho-Tyr522)

Western blot analysis of extracts from JurKat cells using HCK (Phospho-Tyr522) Antibody P40521.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to HCK (Phospho-Tyr522)

货号：
P40521
别名：
p59-HCK/p60-HCK; Hemopoietic cell kinas; Tyrosine-protein kinase HCK;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P08631
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to HCK (Phospho-Tyr522)

Description
The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization

Description

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization

References
Quintrell N., Mol. Cell. Biol. 7:2267-2275(1987) [PubMed: 3496523] Ziegler S.F.,Mol. Cell. Biol. 7:2276-2285(1987) [PubMed: 3453117] Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].

Specification
Aliases	p59-HCK/p60-HCK; Hemopoietic cell kinas; Tyrosine-protein kinase HCK;
Entrez GeneID	3055;
Swissprot	P08631
WB Predicted band size	60kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 522(S-Q-Y(p)-Q-Q) derived from Human HCK .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.