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Western blot analysis of extracts from HepG2 cells treated with PMA using YB1 (Phospho-Ser102) Antibody P40518.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to YB1 (Phospho-Ser102)

货号：
P40518
别名：
CBF-A; NSEP1; EFI-A; MSY-1; YBX1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P67809
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to YB1 (Phospho-Ser102)

Description
YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.Sakura H., Gene 73:499-507(1988)Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988)Kolluri R., Nucleic Acids Res. 19:4771-4771(1991)

Description

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.Sakura H., Gene 73:499-507(1988)Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988)Kolluri R., Nucleic Acids Res. 19:4771-4771(1991)

Specification
Aliases	CBF-A; NSEP1; EFI-A; MSY-1; YBX1
Entrez GeneID	4904;
Swissprot	P67809
WB Predicted band size	36kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.