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Western blot analysis of extracts from RAW264.7 cells treated with UV using MAPKAPK2 (Phospho-Ser272) Antibody P40505.The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPKAPK2 (Phospho-Ser272) antibody P40505 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to MAPKAPK2 (Phospho-Ser272)

  • 货号:

    P40505
  • 别名:

    MAPK2; MAPKAPK2; RPS6KC1;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P49137
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to MAPKAPK2 (Phospho-Ser272)

Description

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.Zu Y.-L., Biochem. Biophys. Res. Commun. 200-1118-1124(1994)The MGC Project Team; Genome Res. 14:2121-2127(2004)Stokoe D., Biochem. J. 296:843-849(1993)

Specification

Aliases MAPK2; MAPKAPK2; RPS6KC1;
Entrez GeneID 9261;
Swissprot P49137
WB Predicted band size 45kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of Serine 272(A-I-S(p)-P-G) derived from Human MAPKAPK2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100