Rabbit Polyclonal Antibody to Girdin (Phospho-Ser1417)

Description
girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.

References
Enomoto A., Dev. Cell 9:389-402(2005) Simpson F., Traffic 6:442-458(2005) Hillier L.W., Nature 434:724-731(2005).

Specification
Aliases	APE; GIV; GRDN; HkRP1; KIAA1212
Entrez GeneID	55704;
Swissprot	Q3V6T2
WB Predicted band size	216kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of Serine 417(Q-K-S(p)-L-T) derived from Human Girdin .
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IHC	1/50-1/100