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Western blot analysis of extracts from Jurkat cells treated with TNF using CtBP1 (Phospho-Ser422) Antibody P40496.The lane on the right is treated with the antigen-specific peptide.

Immunohistochemical analysis of paraffin-embedded human brain tissue, using CtBP1 (Phospho-Ser422) antibody P40496 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to CtBP1 (Phospho-Ser422)

货号：
P40496
别名：
CTBP; C-terminal binding protein 1; EC 1.1.1;
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q13363
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to CtBP1 (Phospho-Ser422)

Description
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995)Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999)The MGC Project Team, Genome Res. 14:2121-2127(2004)

Description

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995)Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999)The MGC Project Team, Genome Res. 14:2121-2127(2004)

Specification
Aliases	CTBP; C-terminal binding protein 1; EC 1.1.1;
Entrez GeneID	1487;
Swissprot	Q13363
WB Predicted band size	48kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.