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Rabbit Polyclonal Antibody to CDC25C (Phospho-Ser198)

Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using CDC25C (Phospho-Ser198) antibody P40490 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to CDC25C (Phospho-Ser198)

货号：
P40490
别名：
CDC25M1; MPI1B; MPIP3; EC 3.1.3.48;
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P30307
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to CDC25C (Phospho-Ser198)

Description
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encode dprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Description

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encode dprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

References
Sadhu K., Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990)Bureik M., Int. J. Oncol. 17:1251-1258(2000)Wegener S., Eur. J. Cell Biol. 79:810-815(2000)

Specification
Aliases	CDC25M1; MPI1B; MPIP3; EC 3.1.3.48;
Entrez GeneID	995;
Swissprot	P30307
WB Predicted band size	53kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 198(E-F-S(p)-L-K) derived from Human CDC25C.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.