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Rabbit Polyclonal Antibody to C/EBP-α (Phospho-Thr230)

Western blot analysis of extracts from cos-7 cells (Lane 2), using C/EBP-α (Phospho-Thr230) Antibody P40488. The lane on the left is treated with antigen-specific peptide.

Rabbit Polyclonal Antibody to C/EBP-α (Phospho-Thr230)

货号：
P40488
别名：
CCAAT/enhancer-binding protein alpha C/EBP alpha CEBPA;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P49715
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to C/EBP-α (Phospho-Thr230)

Description
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Xanthopoulos K.G. Biochem. Biophys. Res. Commun. 215:106-113(1995)Schalwijk J. Biol. Chem. Hoppe-Seyler 378:373-379(1997)SeattleSNPs variation discovery resource Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases

Description

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Xanthopoulos K.G. Biochem. Biophys. Res. Commun. 215:106-113(1995)Schalwijk J. Biol. Chem. Hoppe-Seyler 378:373-379(1997)SeattleSNPs variation discovery resource Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases

Specification
Aliases	CCAAT/enhancer-binding protein alpha C/EBP alpha CEBPA;
Entrez GeneID	1050;
Swissprot	P49715
WB Predicted band size	42kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from Human C/EBP-α.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.