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Immunohistochemical analysis of paraffin-embedded human brain tissue using ATF-2 (Phospho-Ser472) antibody P40485 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to ATF-2 (Phospho-Ser472)

货号：
P40485
别名：
Activating 2; ATF2; cAMP response element binding protein CRE- BP1; CREB2; HB16
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P15336
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to ATF-2 (Phospho-Ser472)

Description
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

References
Maekawa T., EMBO J. 8:2023-2028(1989) Yang L., J. Immunol. 158:2522-2525(1997) Kara C.J., Mol. Cell. Biol. 10:1347-1357(1990).

Specification
Aliases	Activating 2; ATF2; cAMP response element binding protein CRE- BP1; CREB2; HB16
Entrez GeneID	1386;
Swissprot	P15336
WB Predicted band size	54kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 472 (A-L-S(p)-Q-I) derived from Human ATF-2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.