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Rabbit Polyclonal Antibody to FGFR1/2 (Phospho-Tyr463/466)

Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody P40473.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to FGFR1/2 (Phospho-Tyr463/466)

货号：
P40473
别名：
BFGFR; CEK; FLG; CD331; FLT2
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P11362
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to FGFR1/2 (Phospho-Tyr463/466)

Description
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990)Dionne C.A., EMBO J. 9:2685-2692(1990)Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990)

Description

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990)Dionne C.A., EMBO J. 9:2685-2692(1990)Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990)

Specification
Aliases	BFGFR; CEK; FLG; CD331; FLT2
Entrez GeneID	2260;
Swissprot	P11362
WB Predicted band size	91kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of tyrosine 463/466(S-E-Y(p)-E-L) derived from Human FGFR1/2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.