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Western blot analysis of extracts from K562 cells treated with forskolin using HP1γ(Phospho-Ser93) Antibody P40469.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to HP1γ (Phospho-Ser93)

货号：
P40469
别名：
HECH; HP1 gamma; HP1Hs-gamma; chromobox 3;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13185
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to HP1γ (Phospho-Ser93)

Description
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.Ye Q., J. Biol. Chem. 271:14653-14656(1996)Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databasesKoike N., FEBS Lett. 467:17-21(2000)

Description

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.Ye Q., J. Biol. Chem. 271:14653-14656(1996)Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databasesKoike N., FEBS Lett. 467:17-21(2000)

Specification
Aliases	HECH; HP1 gamma; HP1Hs-gamma; chromobox 3;
Entrez GeneID	11335;
Swissprot	Q13185
WB Predicted band size	24kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 93(R-L-S(p)-L-S) derived from Human HP1γ .
Formulation	Purified antibody in PBS with 0.05% sodium azide.