Rabbit Polyclonal Antibody to Connexin 43 (Phospho-Tyr265)

Description
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

References
Toshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725 Toshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519 Masayuki Shimada, Biol Reprod, Apr 2001; 64: 1255 Merry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928.

Specification
Aliases	CX43; CXA1; CXN-43; GJA1;
Entrez GeneID	2697;
Swissprot	P17302
WB Predicted band size	43kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Tyrosine 265(Q-K-Y(p)-A-Y) derived from Human Connexin 43.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000