Rabbit Polyclonal Antibody to Trk B (Phospho-Tyr706/Tyr707)

Description
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

References
Nakagawara A., Genomics 25:538-546(1995)Shelton D.L., J. Neurosci. 15:477-491(1995)Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).

Specification
Aliases	Trk-B; NTRK2; GP145-TrkB;
Entrez GeneID	4915;
Swissprot	Q16620
WB Predicted band size	91kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
IHC	1/50-1/100