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Immunohistochemical analysis of paraffin-embedded human brain tissue using MLK1/2 (Phospho-Thr312/266) antibody P40447 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to MLK1/2 (Phospho-Thr312/266)

货号：
P40447
别名：
M3K9; PRKE1; mixed-lineage protein kinase 1;
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P80192
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to MLK1/2 (Phospho-Thr312/266)

Description
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Durkin J.T., Biochemistry 43:16348-16355(2004)The MGC Project Team; Genome Res. 14:2121-2127(2004)Dorow D.S.,Nature 446:153-158(2007).

Description

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Durkin J.T., Biochemistry 43:16348-16355(2004)The MGC Project Team; Genome Res. 14:2121-2127(2004)Dorow D.S.,Nature 446:153-158(2007).

Specification
Aliases	M3K9; PRKE1; mixed-lineage protein kinase 1;
Entrez GeneID	4293;
Swissprot	P80192
WB Predicted band size	121kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of threonine 312/266(A-G-T(p)-Y-A) derived from Human MLK1/2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.