Rabbit Polyclonal Antibody to MAP3K1 (Phospho-Thr1400)

Description
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway

References
Schmutz J., Nature 431:268-274(2004) Xia Y., Genes Dev. 12:3369-3381(1998) Vinik B.S., Mamm. Genome 6:782-783(1995)

Specification
Aliases	M3K1; MAP3K1; MAPKKK1; MEKK1;
Entrez GeneID	4214;
Swissprot	Q13233
WB Predicted band size	130kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of threonine 1400(K-G-T(p)-G-A) derived from Human MAP3K1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100