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Immunohistochemical analysis of paraffin-embedded human brain tissue using IKK-γ (Phospho-Ser376) antibody P40436 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to IKK-γ (Phospho-Ser376)

货号：
P40436
别名：
FIP3; IKBKG; IKKAP1; IKKG; NF-kappaB
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9Y6K9
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to IKK-γ (Phospho-Ser376)

Description
Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999)Jin D.-Y., J. Biomed. Sci. 6:115-120(1999)Rothwarf D.M., Nature 395:297-300(1998).

Description

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999)Jin D.-Y., J. Biomed. Sci. 6:115-120(1999)Rothwarf D.M., Nature 395:297-300(1998).

Specification
Aliases	FIP3; IKBKG; IKKAP1; IKKG; NF-kappaB
Entrez GeneID	8517;
Swissprot	Q9Y6K9
WB Predicted band size	48kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 376(Y-L-S(p)-S-P) derived from Human IKK-γ.
Formulation	Purified antibody in PBS with 0.05% sodium azide.