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Western blot analysis of extracts from HT-29 cells treated with heat shock using CK-1α (Phospho-Tyr294) Antibody P40432.The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using CK-1α (Phospho-Tyr294) antibody P40432 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to CK-1α (Phospho-Tyr294)

  • 货号:

    P40432
  • 别名:

    KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P48729
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to CK-1α (Phospho-Tyr294)

Description

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994)Fish K.J., J. Biol. Chem. 270:14875-14883(1995)Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases

Specification

Aliases KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I
Entrez GeneID 1452;
Swissprot P48729
WB Predicted band size 37kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1α.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100