提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388787

首页 > 产品中心 > 产品详情

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BLK (Phospho-Tyr501) antibody P40431 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to BLK (Phospho-Tyr501)

货号：
P40431
别名：
p55-BLK; EC 2.7.10.2; kinase Blk; B lymphocyte kinase; Tyrosine-protein kinase BLK
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P51451
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

分享
咨询
收藏

加入购物车

立即购买

Rabbit Polyclonal Antibody to BLK (Phospho-Tyr501)

Description
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Islam K.B., J. Immunol. 154:1265-1272(1995)Drebin J.A.,Oncogene 10:477-486(1995)Greenman C.,Nature 446:153-158(2007).

Description

Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Islam K.B., J. Immunol. 154:1265-1272(1995)Drebin J.A.,Oncogene 10:477-486(1995)Greenman C.,Nature 446:153-158(2007).

Specification
Aliases	p55-BLK; EC 2.7.10.2; kinase Blk; B lymphocyte kinase; Tyrosine-protein kinase BLK
Entrez GeneID	640;
Swissprot	P51451
WB Predicted band size	57kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
Formulation	Purified antibody in PBS with 0.05% sodium azide.