请登录
搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

账号密码登录

微信/QQ登录 微信/QQ登录

没有账号? 立即注册

搜索
Western blot analysis of extracts from COS cells treated with EGF using ABL1 (Phospho-Thr735) Antibody P40429.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to ABL1 (Phospho-Thr735)

  • 货号:

    P40429
  • 别名:

    Abelson murine leukemia viral oncogene 1; ABL1; c-ABL; JTK7; p150
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P00519
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Rabbit Polyclonal Antibody to ABL1 (Phospho-Thr735)

Description

The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. Fainstein E., Oncogene 4:1477-1481(1989)Shtivelman E., Cell 47:277-284(1986)Chissoe S.L., Genomics 27:67-82(1995).

Specification

Aliases Abelson murine leukemia viral oncogene 1; ABL1; c-ABL; JTK7; p150
Entrez GeneID 25;
Swissprot P00519
WB Predicted band size 135kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of threonine735 (S-V-T(p)-L-P) derived from Human ABL1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40429