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Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF1R (Phospho-Tyr1346) antibody P40421 (left)or the same antibody preincubated with blocking peptide (right).
Rabbit Polyclonal Antibody to IGF1R (Phospho-Tyr1346)
-
货号：
P40421 -
别名：
CD221; kinase IGF1R; IGF1R; -
应用：
IHC -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P08069 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to IGF1R (Phospho-Tyr1346)
Description |
|---|
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.Ullrich A., EMBO J. 5:2503-2512(1986)Abbot A.M., J. Biol. Chem. 267:10759-10763(1992)The MGC Project Team;Genome Res. 14:2121-2127(2004) |
Specification |
|
|---|---|
| Aliases | CD221; kinase IGF1R; IGF1R; |
| Entrez GeneID | 3480; |
| Swissprot | P08069 |
| WB Predicted band size | 154kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 1346(Q-P-Y(p)-A-H) derived from Human IGF1R . |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| IHC | 1/50-1/100 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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