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Rabbit Polyclonal Antibody to Nuclear Receptor NR4A1 (Phospho-Ser351)

Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Nuclear Receptor NR4A1 (Phospho-Ser351) antibody P40412 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to Nuclear Receptor NR4A1 (Phospho-Ser351)

货号：
P40412
别名：
NGFIB; GFRP1; HMR; NR4A1; NAK1
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P22736
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to Nuclear Receptor NR4A1 (Phospho-Ser351)

Description
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Nakai A., Mol. Endocrinol. 4:1438-1443(1990)Chang C., J. Steroid Biochem. 34:391-395(1989)Bondy G.P., Cell Growth Differ. 2:203-208(1991)

Description

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Nakai A., Mol. Endocrinol. 4:1438-1443(1990)Chang C., J. Steroid Biochem. 34:391-395(1989)Bondy G.P., Cell Growth Differ. 2:203-208(1991)

Specification
Aliases	NGFIB; GFRP1; HMR; NR4A1; NAK1
Entrez GeneID	3164;
Swissprot	P22736
WB Predicted band size	64kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Serine351(L-P-S(p)-K-P) derived from Human Nuclear Receptor NR4A1.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.