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Rabbit Polyclonal Antibody to TGF β Receptor II (Phospho-Ser225/250)

Immunohistochemical analysis of paraffin-embedded human brain tissue using TGF β Receptor II (Phospho-Ser225/250) antibody P40409 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to TGF β Receptor II (Phospho-Ser225/250)

货号：
P40409
别名：
TGF-betaR2; TGFR2; kinase TGF-beta-R2;
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P37173
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to TGF β Receptor II (Phospho-Ser225/250)

Description
Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. RC Tripathi, Invest. Ophthalmol. Vis. Sci., Jan 1993; 34: 260. N Chegini, Endocrinology, Jul 1994; 135: 439. GW Mulheron, Endocrinology, Dec 1992; 131: 2609

Description

Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. RC Tripathi, Invest. Ophthalmol. Vis. Sci., Jan 1993; 34: 260. N Chegini, Endocrinology, Jul 1994; 135: 439. GW Mulheron, Endocrinology, Dec 1992; 131: 2609

Specification
Aliases	TGF-betaR2; TGFR2; kinase TGF-beta-R2;
Entrez GeneID	7048;
Swissprot	P37173
WB Predicted band size	64kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 225/250(D-R-S(p)-D-I) derived from Human TGF β Receptor II.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.