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Western blot analysis of extracts from JK cells (Lane 2), using hnRPD (Phospho-Ser83) Antibody P40405. The lane on the left is treated with antigen-specific peptide.

Immunofluorescence staining of methanol-fixed HeLa cells using hnRPD (Phospho-Ser83) Antibody P40405.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using hnRPD (Phospho-Ser83) antibody P40405 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to hnRPD (Phospho-Ser83)

货号：
P40405
别名：
ROD; AUF1; HNRPD;
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q14103
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to hnRPD (Phospho-Ser83)

Description
Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

Description

Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

References
Kajita Y., J. Biol. Chem. 270:22167-22175(1995) Dempsey L.A., Genomics 49:378-384(1998) Tolnay M., Biochem. J. 338:417-425(1999) Grosset C., Cell 103:29-40(2000)

Specification
Aliases	ROD; AUF1; HNRPD;
Entrez GeneID	3184;
Swissprot	Q14103
WB Predicted band size	38kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of Serine 83(N-S-S(p)-P-R) derived from Human hnRPD .
Formulation	Purified antibody in PBS with 0.05% sodium azide.