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Western blot analysis of extracts from K562 cells treated with PMA using CD32 (Phospho-Tyr292) Antibody P40386.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to CD32 (Phospho-Tyr292)

货号：
P40386
别名：
CD32; FCG2; FCG2B,; LY-17; CDW32
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P31994
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to CD32 (Phospho-Tyr292)

Description
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989)Brooks D.G., J. Exp. Med. 170:1369-1385(1989)Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990)

Description

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989)Brooks D.G., J. Exp. Med. 170:1369-1385(1989)Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990)

Specification
Aliases	CD32; FCG2; FCG2B,; LY-17; CDW32
Entrez GeneID	2213;
Swissprot	P31994
WB Predicted band size	32kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.
Formulation	Purified antibody in PBS with 0.05% sodium azide.