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Western blot analysis of extracts from HeLa cells treated with TNF using Caspase 9 (Phospho-Thr125) Antibody P40371.The lane on the right is treated with the antigen-specific peptide.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 9 (Phospho-Thr125) antibody P40371 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to Caspase 9 (Phospho-Thr125)

货号：
P40371
别名：
APAF-3; MCH6; RNCASP9; CASP-9; ICE-LAP6
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P55211
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to Caspase 9 (Phospho-Thr125)

Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

References
Duan H., J. Biol. Chem. 271:16720-16724(1996)Srinivasula S.M., J. Biol. Chem. 271:27099-27106(1996)Hadano S., Mamm. Genome 10:757-760(1999)

Specification
Aliases	APAF-3; MCH6; RNCASP9; CASP-9; ICE-LAP6
Entrez GeneID	842;
Swissprot	P55211
WB Predicted band size	47kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of threonine 125 (P-E-T(p)-P-R) derived from Human Caspase 9.
Formulation	Purified antibody in PBS with 0.05% sodium azide.