提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388787

首页 > 产品中心 > 产品详情

Western blot analysis of extracts from HL60 cells using ABL1/2(phospho-Tyr393/439) Antibody P40317 and the same antibody preincubated with blocking peptide.

Immunofluorescence staining of methanol-fixed Hela cells using ABL1/2(phospho-Tyr393/439) Antibody P40317.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ABL1/2(Phospho-Tyr393/439) Antibody P40317(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to ABL1/2 (phospho-Tyr393/439)

货号：
P40317
别名：
Abelson murine leukemia viral oncogene homolog 1; c-ABL; p150
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P00519
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

分享
咨询
收藏

加入购物车

立即购买

Rabbit Polyclonal Antibody to ABL1/2 (phospho-Tyr393/439)

Description
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Description

Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

References
Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259.

Specification
Aliases	Abelson murine leukemia viral oncogene homolog 1; c-ABL; p150
Entrez GeneID	25;
Swissprot	P00519
WB Predicted band size	210kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.