Rabbit Polyclonal Antibody to PLCg2(phospho-Tyr1217)

Description
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

References
Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027. Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. Margolis, B. et al. (1989) Cell 57, 1101-1107.

Specification
Aliases	PLC-IV; PLC-gamma2; Phospholipase C-gamma-2
Entrez GeneID	5336;
Swissprot	P16885
WB Predicted band size	150kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from Human PLCg2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IHC	1/50-1/100