Rabbit Polyclonal Antibody to cofilin1/cofilin2(phospho-Tyr88)

Description
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

References
Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830.Arber, S. et al. (1998) Nature 393, 805-809.Yang, N. et al. (1998) Nature 393, 809-812.

Specification
Aliases	CFL1/CFL2
Entrez GeneID	1072;
Swissprot	P23528
WB Predicted band size	19kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T) derived from Human coflin1/cofilin2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100