Rabbit Polyclonal Antibody to SHP-1(Phospho-Tyr536)

Description
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

References
Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95(7): 3845-3850. Timms JF, et al.(1998) Mol Cell Biol; 18(7): 3838-3850. Kanagasundaram V, et al. (1999) Mol Cell Biol; 19(6): 4079-4092. Hauck CR, et al. (1999) Infect Immun; 67(10): 5490-5494.

Specification
Aliases	70Z-SHP; HCP; HCPH; Hematopoietic cell protein-tyrosine phosphatase; PTN6
Entrez GeneID	5777;
Swissprot	P29350
WB Predicted band size	68kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IHC	1/50-1/100
IF	1/100-1/200