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Western blot analysis of extracts from PC12 cells untreated or treated with PMA using PKCth(Phospho-Ser676) Antibody P40271.

Western blot analysis of extracts from PC12 cells, treated with PMA or calf intestinal phosphatase (CIP), using PKC胃 (Phospho-Ser676) Antibody P40271.

Immunofluorescence staining of methanol-fixed Hela cells using PKCth(Phospho-Ser676) Antibody P40271.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKCth(Phospho-Ser676) Antibody P40271(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to PKCth(Phospho-Ser676)

货号：
P40271
别名：
KPCT; PKC-theta; PKCQ; PRKCQ; PRKCT
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q04759
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to PKCth(Phospho-Ser676)

Description
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production.

References
Kristof Van Kolen, et al. (2006) FEBS J ; 273: 1843 - 1854. Martin Villalba, et al. (2002) J. Cell Biol ; 157: 253. Jie Zhang, et al. (2004) J. Biol. Chem ; 279: 22118 - 22123. Castro AF, et al. (1998) Am J Physiol Cell Physiol; 275: C113 - C119.

Specification
Aliases	KPCT; PKC-theta; PKCQ; PRKCQ; PRKCT
Entrez GeneID	5588;
Swissprot	Q04759
WB Predicted band size	80kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 676 (R-L-S(p)-F-A) derived from Human PKCth.
Formulation	Purified antibody in PBS with 0.05% sodium azide.