Rabbit Polyclonal Antibody to Gab1(Phospho-Tyr627)

Description
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

References
Anders Kallin, et al. (2004) J. Biol. Chem ; 279: 17897 - 17904.Hideto Kameda, et al. (2001) Cell Growth Differ ; 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol ; 158: 773.

Specification
Aliases	Growth factor receptor bound protein 2-associated protein 1
Entrez GeneID	2549;
Swissprot	Q13480
WB Predicted band size	110kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D) derived from Human Gab1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IF/ICC	1/100-1/200