Rabbit Polyclonal Antibody to BIM(Phospho-Ser69)

Description
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis

References
Fukazawa H, et al. (2004) Mol Cancer Ther ; 3(10): 1281-1288Luciano F, et al. (2003) Oncogene ; 22(43): 6785-6793

Specification
Aliases	BCL2-like protein 11; BCL2L11; BOD; Bcl-2 related ovarian death protein;
Entrez GeneID	10018;
Swissprot	O43521
WB Predicted band size	23kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G) derived from Human BIM.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IHC	1/50-1/100
IF	1/100-1/200