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Western blot analysis of extracts from Jurkat cells untreated or treated with insulin using p56Dok-2(Phospho-Tyr299) Antibody P40255.
Western blot analysis of extracts from JK cells, treated with G-CSF or calf intestinal phosphatase (CIP), using p56Dok-2 (Phospho-Tyr299) Antibody P40255.
Immunofluorescence staining of methanol-fixed Hela cells using p56Dok-2(Phospho-Tyr299) Antibody P40255.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p56Dok-2(Phospho-Tyr299) Antibody P40255(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p56Dok-2(Phospho-Tyr299)

  • 货号:

    P40255
  • 别名:

    DOK2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O60496
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to p56Dok-2(Phospho-Tyr299)

Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

References

Feng Cong, et,al. (1999) Mol. Cell. Biol ; 19: 8314 - 8325. Serge Lemay, et,al. (2000) Mol. Cell. Biol ; 20: 2743 - 2754. Ute Schaeper, et,al.(2000) J. Cell Biol ; 149: 1419. Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151.

Specification

Aliases DOK2
Entrez GeneID 9046;
Swissprot O60496
WB Predicted band size 56kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200