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Western blot analysis of extracts from K562 cells untreated or treated with H2O2 using p62Dok(phospho-Tyr398) Antibody P40254.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok(Phospho-Tyr398) Antibody P40254(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p62Dok(phospho-Tyr398)

货号：
P40254
别名：
DOK1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99704
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to p62Dok(phospho-Tyr398)

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

References
Michael J. Wick, et al. (2001) J. Biol. Chem ; 276: 42843 - 42850.Paul D. Simoncic, et al. (2006) Mol. Cell. Biol ; 26: 4149 - 4160.Nadia Dub

Specification
Aliases	DOK1
Entrez GeneID	1796;
Swissprot	Q99704
WB Predicted band size	62kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 398 (E-G-Y(p)-E-L) derived from Human p62Dok.
Formulation	Purified antibody in PBS with 0.05% sodium azide.