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Rabbit Polyclonal Antibody to p62Dok(phospho-Tyr362)

Western blot analysis of extracts from Jurkat cells untreated or treated with insulin using p62Dok(phospho-Tyr362) Antibody P40253.

Western blot analysis of extracts from JK cells, treated with G-CSF or calf intestinal phosphatase (CIP), using p62Dok (phospho-Tyr362) Antibody P40253.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok(Phospho-Tyr362) Antibody P40253(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p62Dok(phospho-Tyr362)

货号：
P40253
别名：
DOK1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q99704
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to p62Dok(phospho-Tyr362)

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

References
Zhou Songyang, et al. (2001) J. Biol. Chem ; 276: 2459 - 2465. Jean-Guy N

Specification
Aliases	DOK1
Entrez GeneID	1796;
Swissprot	Q99704
WB Predicted band size	62kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of tyrosine 362 (P-I-Y(p)-D-E) derived from Human p62Dok.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.