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Western blot analysis of extracts from MCF cells untreated or treated with EGF using p70 S6 Kinase(Phospho-Ser411) Antibody P40249.

Immunofluorescence staining of methanol-fixed MCF7 cells using p70 S6 Kinase(Phospho-Ser411) Antibody P40249.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase(Phospho-Ser411) Antibody P40249(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Ser411)

货号：
P40249
别名：
KS6B1; P70-S6K; RPS6KB1; S6K;
产品上架时间：
2024-04-03
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P23443
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Ser411)

Description
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.

References
Satoru Eguchi et al. (1999) J Biol Chem, Vol. 274: 36843-36851Papst PJ, et al. (1998) J Biol Chem. 273(24):15077-84.Ulrike Krause et al. (2002) Eur. J. Biochem. 269: 3751-3759 cLe, X.F, et al. (2003) Oncogene 22: 484

Specification
Aliases	KS6B1; P70-S6K; RPS6KB1; S6K;
Entrez GeneID	6198;
Swissprot	P23443
WB Predicted band size	70 85 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 411 (I-R-S(p)-P-R) derived from Human p70 S6 Kinase.
Formulation	Purified antibody in PBS with 0.05% sodium azide.