Rabbit Polyclonal Antibody to Connexin 43 (phospho-Ser368)

Description
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

References
Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211 Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353, Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654 W. E. I. Li, et al.(1998) European Journal of Neuroscience 10: 2444

Specification
Aliases	CX43; CXA1; CXN-43; GJA1;
Entrez GeneID	2697;
Swissprot	P17302
WB Predicted band size	43kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 368 (R-A-S(p)-S-R) derived from Human Connexin 43.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100