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Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Thr421)
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货号:
P40236 -
别名:
KS6B1; P70-S6K; RPS6KB1; S6K; -
应用:
WB,IHC,IF -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P23443 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Thr421)
Description |
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Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation. |
References |
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Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497An WL, et al. (2003) Am J Pathol. 163(2): 591-607.Le XF, et al. (2003) Oncogene.22(4): 484-97 |
Specification |
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Aliases | KS6B1; P70-S6K; RPS6KB1; S6K; |
Entrez GeneID | 6198; |
Swissprot | P23443 |
WB Predicted band size | 70 85 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of threonine 421 (P-R-T(p)-P-V) derived from Human p70 S6 Kinase. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/100-1/200 |
Product Image
- Western blot analysis of extracts from Jurkat cells untreated(lane 1) or treated with GM-CSF(lane 2) using p70 S6 Kinase(Phospho-Thr421) Antibody P40236.
- Immunofluorescence staining of methanol-fixed MCF cells using p70 S6 Kinase(Phospho-Thr421) Antibody P40236.
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase(Phospho-Thr421) Antibody P40236(left) or the same antibody preincubated with blocking peptide(right).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P40236

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