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Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Thr421)

Western blot analysis of extracts from Jurkat cells untreated(lane 1) or treated with GM-CSF(lane 2) using p70 S6 Kinase(Phospho-Thr421) Antibody P40236.

Immunofluorescence staining of methanol-fixed MCF cells using p70 S6 Kinase(Phospho-Thr421) Antibody P40236.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase(Phospho-Thr421) Antibody P40236(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Thr421)

货号：
P40236
别名：
KS6B1; P70-S6K; RPS6KB1; S6K;
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P23443
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to p7S6 Kinase(Phospho-Thr421)

Description
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.

References
Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497An WL, et al. (2003) Am J Pathol. 163(2): 591-607.Le XF, et al. (2003) Oncogene.22(4): 484-97

Specification
Aliases	KS6B1; P70-S6K; RPS6KB1; S6K;
Entrez GeneID	6198;
Swissprot	P23443
WB Predicted band size	70 85 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine 421 (P-R-T(p)-P-V) derived from Human p70 S6 Kinase.
Formulation	Purified antibody in PBS with 0.05% sodium azide.