Rabbit Polyclonal Antibody to Raf1(Phospho-Ser338)

Description
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

References
Adams DG,et al. (2005)J Biol Chem. 280(52):42644-54.Miura S, et al. (2003) Biochem Biophys Res Commun. 306(4):924-9.Noser JA,et al.(2007)Mol Ther.15(8):1531-6.

Specification
Aliases	C-RAF; C-Raf; CRAF
Entrez GeneID	5894;
Swissprot	P04049
WB Predicted band size	73kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 338 (R-D-S(p)-S-Y) derived from Human RAF.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000