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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using PSCA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of PC-3 cells using PSCA mouse mAb (green) and negative control (red).

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Mouse Monoclonal Antibody to PSCA

货号：
32058
别名：
PRO232
产品上架时间：
2024-01-01
应用：
IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O43653
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to PSCA

Description
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

Description

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

References
1.Biosci Rep. 2019 Sep 3;39(9):BSR20181025. 2.Cancer Prev Res (Phila). 2019 Sep;12(9):579-584.

Specification
Aliases	PRO232
Entrez GeneID	8000
Swissprot	O43653
clone	5H5A7
WB Predicted band size	12kDa
Host/Isotype	Mouse IgG2a
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human PSCA (AA: 1-114) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide