Rabbit Polyclonal Antibody to Bcr(Phospho-Tyr177)

Description
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

References
Sattler M, et al. Mol Cell Biol. 1999 Nov; 19(11): 7473-7480.Li S et al. EMBO J. 2001 Dec 3; 20(23): 6793-6804.Million RP, et,al. Mol Cell Biol. 2004 Jun; 24(11): 4685-4695.Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907

Specification
Aliases	BCR; BCR protein; BCR1
Entrez GeneID	613;
Swissprot	P11274
WB Predicted band size	210kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N) derived from Human Bcr.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100