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Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)
Western blot analysis of extract from Hela cells untreated or treated with serum using IkB-a(Phospho-Tyr42) antibody P40156.
Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-a(phospho-Tyr42) antibody(P40156).
Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)
Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)

Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)

  • 货号:

    P40156
  • 别名:

    IKBA; MAD-3; NFKBI; NFKBIA;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P25963
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)

Description

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

References

B

Specification

Aliases IKBA; MAD-3; NFKBI; NFKBIA;
Entrez GeneID 4792;
Swissprot P25963
WB Predicted band size 39kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IkB-a
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40156