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Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)
-
货号:
P40156 -
别名:
IKBA; MAD-3; NFKBI; NFKBIA; -
应用:
WB,IHC -
反应种属:
Human,Mouse -
抗体类型:
Primary antibody -
Swissprot:
P25963 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Rabbit Polyclonal Antibody to IkB-a(Phospho-Tyr42)
Description |
|---|
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription. |
References |
|---|
| B |
Specification |
|
|---|---|
| Aliases | IKBA; MAD-3; NFKBI; NFKBIA; |
| Entrez GeneID | 4792; |
| Swissprot | P25963 |
| WB Predicted band size | 39kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IkB-a |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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