提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388787

首页 > 产品中心 > 产品详情

Western blot analysis of extracts from Hela cells untreated or treated with TNF using IkB-a(Phospho-Ser32/Ser36) Antibody P40147.

Immunofluorescence staining of methanol-fixed Hela cells using IkB-a(Phospho-Ser32/Ser36) Antibody P40147.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-a(Phospho-Ser32/Ser36) Antibody P40147(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to IkB-a(Phospho-Ser32/Ser36)

货号：
P40147
别名：
I-kappa-B-alpha; IKBA; NF-kappaB inhibitor alpha; NFKBI; NFKBIA
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P25963
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

分享
咨询
收藏

加入购物车

立即购买

Rabbit Polyclonal Antibody to IkB-a(Phospho-Ser32/Ser36)

Description
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

References
Shieh, S. Y. et al. (1999) EMBO J. 18, 1815-1823.Honda, R. et al. (1997) FEBS Lett. 420, 25-27.Hirao, A. et al. (2000) Science 287, 1824-1827.Tibbetts, R. S. et al. (1999) Genes Dev. 13, 152-157.Chehab,N.H.et al. (1999) Proc .Natl .Acad. Sci. USA 96, 13777-13782.

Specification
Aliases	I-kappa-B-alpha; IKBA; NF-kappaB inhibitor alpha; NFKBI; NFKBIA
Entrez GeneID	4792;
Swissprot	P25963
WB Predicted band size	39kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of serine 32/36 (H-D-S(p)-G-L-D-S(p)-M-K) derived from Human IkB-a.
Formulation	Purified antibody in PBS with 0.05% sodium azide.